Our Work

What's Changed Cli improvement by @Marina18 in https://github.com/ersilia-os/ersilia/pull/1846 Ersilia improvements by @Marina18 in https://github.com/ersilia-os/ersilia/pull/1876 Add CC-BY-NC-ND-4.0…

What's Changed Cli improvement by @Marina18 in https://github.com/ersilia-os/ersilia/pull/1846 Ersilia improvements by @Marina18 in https://github.com/ersilia-os/ersilia/pull/1876 Add CC-BY-NC-ND-4.0 to accepted license list by @arnaucoma24 in https://github.com/ersilia-os/ersilia/pull/1884 Drop Py3.8 and Py3.9, harden eval, add license check and serve close fix by @Marina18 in https://github.com/ersilia-os/ersilia/pull/1890 New Contributors @arnaucoma24 made their first contribution in https://github.com/ersilia-os/ersilia/pull/1884 Full Changelog: https://github.com/ersilia-os/ersilia/compare/v0.1.58...v0.1.61

We present the case of a 23-month-old male with a one-year history of intermittent abdominal pain who presented for aroutine well-child visit and was incidentally noted to have a large abdominal mass …

We present the case of a 23-month-old male with a one-year history of intermittent abdominal pain who presented for aroutine well-child visit and was incidentally noted to have a large abdominal mass and regression of developmentalmilestones. Upon further investigation, the child was diagnosed with Wilms Tumor (WT) with metastases to the periaortic lymph nodes and bilateral lungs. Initial management included left radical nephrectomy, lymphadenectomy, andmediport placement for chemotherapy infusions. Tumor cytogenetic report was positive for loss of heterozygosity at11p15 region and pathology demonstrated blastema predominant WT. Treatment decision was based on a therapeuticclinical trial (AREN0534) outlined by the Children’s Oncology Group and the patient was placed on a 28-week chemotherapy regimen, including vincristine, dactinomycin, doxorubicin, cyclophosphamide, carboplatin, and etoposide in conjunction with radiation. MRI of the head showed no evidence of metastasis, however it demonstrated multiple areas ofinfarction in the distribution of the posterior cerebral artery (PCA). Coagulation studies were performed to evaluate possible underlying causes and the patient was found to be heterozygous for Factor V Leiden (FVL) mutation. While FVL isassociated with an increased risk of venous thromboembolic (VTE) events, arterial thromboembolic events are generallyrare. In this report, we explore potential etiologies for the unique presentation of brain infarction in a pediatric patientwith WT.

Work is accomplished by hydraulic machines using liquid fluid power. A typical example is heavy construction equipment. The hydraulic fluid in this kind of machine is pushed to numerous hydraulic moto…

Work is accomplished by hydraulic machines using liquid fluid power. A typical example is heavy construction equipment. The hydraulic fluid in this kind of machine is pushed to numerous hydraulic motors and hydraulic cylinders located all around the machine and are pressured in accordance with the resistance present. Through hoses, tubes, or pipes, the fluid is distributed and is directly or automatically regulated by control valves. With applications and significant ramifications for many industrial, civil, and environmental engineering problems, hydraulic dynamics is developing as a fundamental topic.

Background: Mediastinal hemangiomas are extremely rare benign vascular neoplasms, accounting for less than 0.5% of all diagnosed mediastinal masses. Primary origin from or direct involvement of the wa…

Background: Mediastinal hemangiomas are extremely rare benign vascular neoplasms, accounting for less than 0.5% of all diagnosed mediastinal masses. Primary origin from or direct involvement of the walls of the right superior vena cava (SVC) is exceptionally uncommon. We present the case of a 31-year-old man with a 6-month history of recurrent upper respiratory tract infections. Chest radiography showed displacement of the tracheal midline, and noncontrast computed tomography demonstrated a large anterior mediastinal tumor arising from the right SVC. Complete surgical excision was performed through an open transthoracic approach to ensure safe vascular control. Intraoperative findings included abundant thymic fat, multiple dense fibrous adhesions, and a 5 × 6 cm tumor involving the superior jugular vein, right pleura, and pericardium, as well as periaortic neovascularization. Definitive histopathologic examination confirmed a cavernous hemangioma with dystrophic calcification arising in residual thymic and adipose tissue and showed positive surgical margins (R1 resection) in the specimens from the mediastinal tumor, the SVC extension, and the periaortic tissue. Because of the absence of a true fibrous capsule and the lesion’s intimate fusion with the adventitia of the great vessels, achieving microscopically negative margins (R0) is highly challenging when preservation of vascular structural integrity is prioritized. Therefore, after an R1 resection, although the benign nature of the lesion precludes metastatic potential, strict long-term clinical and imaging surveillance with serial CT scans is required to monitor for possible local recurrence. Keywords: Cavernous hemangioma, Anterior mediastinum, Superior vena cava, Surgical margins, Vascular control.

A 13-y-old girl presented with complaints of cough, cold, and fever for 3 days; she was considered as a case of viral rhinitis. As her pulses were feeble on examination, she was admitted and was found…

A 13-y-old girl presented with complaints of cough, cold, and fever for 3 days; she was considered as a case of viral rhinitis. As her pulses were feeble on examination, she was admitted and was found to have weak pulses all over. Prior to thisshe was asymptomatic. Her aortogram revealed multiple stenoses of major arteries of thorax and upper limbs. She wasdiagnosed to have Takayasu arteritis.

This paper develops a mathematical model of the change in load mass during the operation of a trailer lifting-tipping device. Five characteristic positions of the load in the body during unloading are…

This paper develops a mathematical model of the change in load mass during the operation of a trailer lifting-tipping device. Five characteristic positions of the load in the body during unloading are considered. Calculated dependencies are obtained for each position and combined into a system of equations with boundary conditions.

This repository hosts the official Python machine learning pipeline and computational code for forecasting longitudinal overweight and paediatric obesity prevalence trends among four-year-old children…

This repository hosts the official Python machine learning pipeline and computational code for forecasting longitudinal overweight and paediatric obesity prevalence trends among four-year-old children in Hong Kong. Utilising open public health data provided by the Department of Health via DATA.GOV.HK (covering 2011–2025), this codebase provides an end-to-end workflow comparing conventional machine learning algorithms against Explainable AI (XAI) and statistical architectures: Predictive & Trend Models: Random Forest Regressor, XGBoost Regressor, and Polynomial Trend Forecasting. Statistical & Explainable AI (XAI) Models: Generalised Additive Models (GAMs via pygam) and Explainable Boosting Machines (EBM via interpret). Code Structure & Functionality: Data Preprocessing & Encoding: Automated routines for reshaping longitudinal health data, missing value handling, and categorical feature dummy encoding. Model Training & Evaluation: K-Fold cross-validation evaluating algorithms across R square score and Mean Absolute Error (MAE) metrics. Gender Stratification: Subgroup execution for cohort analysis (Boys vs. Girls) to account for differing trajectory patterns. Automated Output Generation: Integrated plotting routines (seaborn/matplotlib) and automated export of performance summary tables and trend extrapolation graphics.

 The article focuses on the basic principles and methods of seismic protection. Special attention is paid to the issues of ensuring the resistance of buildings to seismic hazards by modern seismi…

 The article focuses on the basic principles and methods of seismic protection. Special attention is paid to the issues of ensuring the resistance of buildings to seismic hazards by modern seismic protection systems, the selection of building materials and the development of constructive solutions. The article is intended for design engineers, construction specialists and scientists involved in seismic safety issues.  

Abstract: We establish a universal mathematical theorem and verified computational suite for aligning arbitrary physical noise to a common logical action across general stabilizer architectures. For a…

Abstract: We establish a universal mathematical theorem and verified computational suite for aligning arbitrary physical noise to a common logical action across general stabilizer architectures. For any [[n,k,d]] stabilizer code encoding a K=2^k dimensional logical system via isometry W: \mathcal{H}_L \rightarrow \mathcal{H}_P, and defining the correction radius t = \lfloor(d-1)/2\rfloor, every completely positive trace-preserving (CPTP) Stinespring noise process supported on any selected set of at most t physical qubits is proved to be exactly correctable. Rather than presupposing pre-aligned Kraus branches, the framework expands local physical operators in the complete Pauli basis, derives the Knill-Laflamme scalar matrix from code distance, and Gram-diagonalizes the resulting error-image matrix. This constructs orthogonal syndrome isometries Q_r that satisfy the derived common-action identity: Q_r^\dagger A_\mu W = \beta_{\mu r} I_L This dynamic factorization separates the logical state from the syndrome and environment: (D \otimes I_E) V W |\psi\rangle = |\psi\rangle_L \otimes |\Xi\rangle_{SE} The recovery identity \mathcal{R} \circ \mathcal{N} \circ \text{Enc} = \text{Enc} is rigorously validated across operator spaces, ancilla-complete entanglements, arbitrary-depth circuits, and generator-level suppression of local GKSL dynamics (\mathcal{R}_L[\mathcal{L}_{\text{phys}}(\text{Enc}(\rho_L))] = 0). A centered physical channel featuring distinct branches (I, X_q, Z_q) and amplitudes (1/3, +2/3, -2/3) provides an exact squared completeness of 1/9 + 4/9 + 4/9 = 1. The accompanying open-source NumPy suite (tibedo_v4_arbitrary_qubit_alignment_suite.py) provides an executable certification engine for arbitrary user-supplied stabilizer generators. Evaluated on the [[5,1,3]] perfect code and [[7,1,3]] Steane code, all 16 core theorem tests passed alongside 64 randomized stress trials through corrected circuit depth 32, yielding pristine residuals ranging from 2.22 \times 10^{-16} to 3.03 \times 10^{-14}. As the theorem proves, the commercial opportunity for a quantum sector shifts entirely from physical manufacturing to the epistemological layer: mastery over problem representation and architectural compilation. Without this specialized knowledge, a hardware firm possessing a theoretically fault-tolerant physical machine is left with an empty shell—an advanced engine with no operational map. They are entirely dependent on the underlying mathematical framework to achieve exact circuit closure (\mathcal{R} \circ \mathcal{N} \circ \text{Enc} = \text{Enc}) and generator-level suppression of arbitrary local GKSL data (\mathcal{R}_L[\mathcal{L}_{\text{phys}}(\text{Enc}(\rho_L))] = 0). True commercial leverage and sales dominance concentrate within the hands of entities that command the mathematical representation layer. Knowledge of how to structure error-correcting codes, derive syndrome isometries without heuristic Kraus proportionalities, and preserve logical coherence across arbitrary circuit depths becomes the ultimate arbiter of value in the post-NISQ economy.